About

I am an Assistant Professor in the Department of Health and Society at the University of Toronto Scarborough. My research is situated at the intersection of data science and public health.

I received my Ph.D in Biostatistics from Vanderbilt University in 2018. You can check out my mathematics academic genealogy here .

After my graduate studies, I was a postdoc in the Center for Precision Medicine in the Department of Biomedical Informatics at Vanderbilt University Medical Center. Prior to joining UTSC, I was a Research Fellow and founding member of the Precision Health Informatics Section at the National Human Genome Research Institute, National Institutes of Health in Bethesda, MD.

Office
HL 228
Address
1265 Military Trail • University of Toronto Scarborough • Toronto, ON M1C 1A4
Email
david.schlueter@utoronto.ca

Research

My research broadly focuses on the usage of electronic health records for public health scientific discovery, development of novel statistical techniques, and genomic science.
Electronic health records are composed of a rich variety of data types which are collected routinely as part of clinical care. These data types, coupled with temporal information allow us to study in detail how disease risk changes over time.

Using EHR to study disease allows definitions of outcomes that would previously have been difficult to ascertain. Furthermore, with the advent of large human genomic databases such as the All of Us Research program in the United States and the UK Biobank, genomic data coupled with EHR provides a powerful data source for scientific discovery.

Public Health Discovery Using Biobanks

A central source of data in my research involves federated national biobanks such as the All of Us Research Program in the United States. This particular data source pools together electronic health records from contributing health systems from over 300 sites with the stated goal of amassing a dataset of over a million participants to further precision medicine. This dataset comprises data from EHR, wearables, surveys, and genetic information to provide researchers with multifaceted data for discovery. Pertaining to this work, I am affiliated with the Precision Health Informatics Section at the National Institutes of Health as a special volunteer.

Development of Novel Statistical Methodology

Risk of disease changes over time and as a function of independent factors such as demographic factors, lifestyle, genetics, and environment. A key component of my research involves development of time-to-event (a.k.a. survival analysis models) to model risk of disease over time.

Genomic Discovery

Genetics comprise the blueprint of human life and often play a key role in the development of disease. Using whole-genome sequencing, my research involves the discovery of genetic markers and associations with diseases such as endometriosis and uterine fibroids.

Health Disparities Research

As defined by the US CDC, health disparities are inequitable differences in healthcare which are "directly related to the historical and current unequal distribution of social, political, economic, and environmental resources". Disparities in healthcare exacerbate disease and put an unequal burden of disease under-represented minorities. A focus of my research involves studying how clinical outcomes differ among traditionally under-represented populations.



For a full list of my publications, please see my CV above as well as my Google Scholar page.

Teaching

I have taught various graduate and undergraduate courses
in biostatistics and epidemiology.

Current courses:

HLTB30 Current Issues in Health, University of Toronto
HLTC27 Community Health and Epidemiology, University of Toronto

Media

My joint work with colleagues has been covered by
several newspapers and media organizations.

New York Times: Scientists Report Earliest Known Coronavirus Infections in Five U.S. States

Washington Post: NIH study suggests coronavirus may have been in U.S. as early as December 2019

CNN: NIH researchers find more evidence Covid was circulating in the US in December 2019

Personal

Outside of work, I enjoy running, listening to heavy metal, and
playing Magic the Gathering.
I am married to Dr. Shohini Bhattasali.